Ontology highlight
ABSTRACT:
SUBMITTER: Naumann EA
PROVIDER: S-EPMC2846983 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Naumann Eva A EA Kampff Adam R AR Prober David A DA Schier Alexander F AF Engert Florian F
Nature neuroscience 20100321 4
Existing techniques for monitoring neural activity in awake, freely behaving vertebrates are invasive and difficult to target to genetically identified neurons. We used bioluminescence to non-invasively monitor the activity of genetically specified neurons in freely behaving zebrafish. Transgenic fish with the Ca(2+)-sensitive photoprotein green fluorescent protein (GFP)-Aequorin in most neurons generated large and fast bioluminescent signals that were related to neural activity, neuroluminescen ...[more]