Ontology highlight
ABSTRACT:
SUBMITTER: Hsieh YJ
PROVIDER: S-EPMC2847643 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Hsieh Yi-Ju YJ Wanner Barry L BL
Current opinion in microbiology 20100218 2
This review concerns how Escherichia coli detects environmental inorganic orthophosphate (P(i)) to regulate genes of the phosphate (Pho) regulon by the PhoR/PhoB two-component system (TCS). P(i) control by the PhoR/PhoB TCS is a paradigm of a bacterial signal transduction pathway in which occupancy of a cell surface receptor(s) controls gene expression in the cytoplasm. The P(i) signaling pathway requires seven proteins, all of which probably interact in a membrane-associated signaling complex. ...[more]