Interaction fidelity in two-component signaling.
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ABSTRACT:
SUBMITTER: Szurmant H
PROVIDER: S-EPMC2847666 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Publications
Interaction fidelity in two-component signaling.
Szurmant Hendrik H Hoch James A JA
Current opinion in microbiology 20100203 2
Two component signal transduction systems and phosphorelays have been adapted and amplified by bacteria to respond to a multitude of environmental, metabolic and cell cycle signals while maintaining essentially identical structures for the domains responsible for recognition and phosphotransfer between the sensor histidine kinase and the response regulator. Co-crystal structures of these domains have revealed the variable residues at the interaction surface of the two components responsible for ...[more]
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