Integrating phenotype ontologies across multiple species.
Ontology highlight
ABSTRACT:
SUBMITTER: Mungall CJ
PROVIDER: S-EPMC2847714 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Publications
Integrating phenotype ontologies across multiple species.
Mungall Christopher J CJ Gkoutos Georgios V GV Smith Cynthia L CL Haendel Melissa A MA Lewis Suzanna E SE Ashburner Michael M
Genome biology 20100108 1
Phenotype ontologies are typically constructed to serve the needs of a particular community, such as annotation of genotype-phenotype associations in mouse or human. Here we demonstrate how these ontologies can be improved through assignment of logical definitions using a core ontology of phenotypic qualities and multiple additional ontologies from the Open Biological Ontologies library. We also show how these logical definitions can be used for data integration when combined with a unified mult ...[more]
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