Phenotype ontologies for mouse and man: bridging the semantic gap.
Ontology highlight
ABSTRACT:
SUBMITTER: Schofield PN
PROVIDER: S-EPMC2860848 | biostudies-literature | 2010 May-Jun
REPOSITORIES: biostudies-literature
Publications
Phenotype ontologies for mouse and man: bridging the semantic gap.
Schofield Paul N PN Gkoutos Georgios V GV Gruenberger Michael M Sundberg John P JP Hancock John M JM
Disease models & mechanisms 20100501 5-6
A major challenge of the post-genomic era is coding phenotype data from humans and model organisms such as the mouse, to permit the meaningful translation of phenotype descriptions between species. This ability is essential if we are to facilitate phenotype-driven gene function discovery and empower comparative pathobiology. Here, we review the current state of the art for phenotype and disease description in mice and humans, and discuss ways in which the semantic gap between coding systems migh ...[more]
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