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NetPath: a public resource of curated signal transduction pathways.


ABSTRACT: We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches.

SUBMITTER: Kandasamy K 

PROVIDER: S-EPMC2847715 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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NetPath: a public resource of curated signal transduction pathways.

Kandasamy Kumaran K   Mohan S Sujatha SS   Raju Rajesh R   Keerthikumar Shivakumar S   Kumar Ghantasala S Sameer GS   Venugopal Abhilash K AK   Telikicherla Deepthi D   Navarro J Daniel JD   Mathivanan Suresh S   Pecquet Christian C   Gollapudi Sashi Kanth SK   Tattikota Sudhir Gopal SG   Mohan Shyam S   Padhukasahasram Hariprasad H   Subbannayya Yashwanth Y   Goel Renu R   Jacob Harrys K C HK   Zhong Jun J   Sekhar Raja R   Nanjappa Vishalakshi V   Balakrishnan Lavanya L   Subbaiah Roopashree R   Ramachandra Y L YL   Rahiman B Abdul BA   Prasad T S Keshava TS   Lin Jian-Xin JX   Houtman Jon C D JC   Desiderio Stephen S   Renauld Jean-Christophe JC   Constantinescu Stefan N SN   Ohara Osamu O   Hirano Toshio T   Kubo Masato M   Singh Sujay S   Khatri Purvesh P   Draghici Sorin S   Bader Gary D GD   Sander Chris C   Leonard Warren J WJ   Pandey Akhilesh A  

Genome biology 20100112 1


We have developed NetPath as a resource of curated human signaling pathways. As an initial step, NetPath provides detailed maps of a number of immune signaling pathways, which include approximately 1,600 reactions annotated from the literature and more than 2,800 instances of transcriptionally regulated genes - all linked to over 5,500 published articles. We anticipate NetPath to become a consolidated resource for human signaling pathways that should enable systems biology approaches. ...[more]

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