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PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila.

ABSTRACT: An Aeromonas allosaccharophila environmental isolate recovered from the Seine River (Paris, France) produced a novel extended-spectrum beta-lactamase, PER-6, that shared 92% amino acid identity with the closest ss-lactamase, PER-2. The kinetic properties of PER-6 showed a slightly increased affinity for carbapenems. The bla(PER-6) gene was chromosomally located and bracketed by non-transposon-related structures.

SUBMITTER: Girlich D

PROVIDER: S-EPMC2849380 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature

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PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila.

Girlich Delphine D Poirel Laurent L Nordmann Patrice P

Antimicrobial agents and chemotherapy 20100209 4

An Aeromonas allosaccharophila environmental isolate recovered from the Seine River (Paris, France) produced a novel extended-spectrum beta-lactamase, PER-6, that shared 92% amino acid identity with the closest ss-lactamase, PER-2. The kinetic properties of PER-6 showed a slightly increased affinity for carbapenems. The bla(PER-6) gene was chromosomally located and bracketed by non-transposon-related structures. ...[more]

PMID: 20145085

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