Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC2850942 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Zhang Jianjun J Dhakal Ishwori B IB Greene Graham G Lang Nicholas P NP Kadlubar Fred F FF
Urology 20091114 4
<h4>Objectives</h4>To investigate whether polymorphisms in genes involved in the repair of oxidative DNA damage, modulate, and/or interact with antioxidants to influence prostate cancer risk in a population-based case-control study in Central Arkansas. Accumulating evidence indicates that oxidative stress plays a role in prostate carcinogenesis.<h4>Methods</h4>Cases (n = 193) included men aged 40-80 years, diagnosed with prostate cancer in 3 major hospitals in 1998-2003, and controls (n = 197) w ...[more]