Ontology highlight
ABSTRACT:
SUBMITTER: Sarkar A
PROVIDER: S-EPMC2853252 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Virology 20100305 1
To gain insight into the structural and functional properties of the vesicular stomatitis virus nucleocapsid-RNA complex (vN-RNA), we analyzed it by treatment with proteolytic enzymes. Chymotrypsin treatment to the vN-RNA results in complete digestion of the C-terminal 86 amino acids of the N protein. The residual chymotrypsin resistant vN-RNA complex (vDeltaN-RNA) carrying N-terminal 336 amino acids of the N protein (DeltaN) was inactive in transcription. The DeltaN protein retained its capabil ...[more]