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Respiratory cryptosporidiosis in HIV-seronegative children in Uganda: potential for respiratory transmission.


ABSTRACT:

Background

Respiratory cryptosporidiosis is recognized as a late-stage complication in persons with human immunodeficiency virus (HIV) infection and AIDS. However, respiratory signs and symptoms are common in otherwise healthy children with intestinal cryptosporidiosis, which suggests that respiratory infection may occur in immunocompetent hosts.

Methods

We recruited children 9-36 months of age who presented with diarrhea to Mulago Hospital in Kampala, Uganda, from November 2007 through January 2009. Children with stool samples positive or negative for Cryptosporidium species were selected for further evaluation, including sputum induction in those with cough or unexplained respiratory signs and collection of saliva and blood specimens. Sputum samples were subjected to compr

SUBMITTER: Mor SM 

PROVIDER: S-EPMC2856758 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature