Ontology highlight
ABSTRACT:
SUBMITTER: Welman A
PROVIDER: S-EPMC2857038 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Welman Arkadiusz A Serrels Alan A Brunton Valerie G VG Ditzel Mark M Frame Margaret C MC
The Journal of biological chemistry 20100205 15
We report the development and application of photoactivatable Green Cherry (G(PA)C), the first genetically encoded "continuously red-photoactivatable green" two-color probe for live cell imaging. G(PA)C is unique in that it enables real-time tracking of selected subpopulations of proteins and organelles in the cell or of cells within tissues and whole organisms, with constant reference to the entire population of the probe. Using G(PA)C-zyxin as proof of utility, we obtained new insights into th ...[more]