Ontology highlight
ABSTRACT:
SUBMITTER: Gutierrez M
PROVIDER: S-EPMC2859090 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Journal of natural products 20100401 4
Fractionation of the extract of the marine cyanobacterium Lyngbya majuscula collected from Panama led to the isolation of malyngolide dimer (1). The planar structure of 1 was determined using 1D and 2D NMR spectroscopy and HRESI-TOFMS. The absolute configuration was established by chemical degradation followed by chiral GC-MS analyses and comparisons with an authentic sample of malyngolide seco-acid (4). Compound 1 showed moderate in vitro antimalarial activity against chloroquine-resistant Plas ...[more]