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Fused tetrazoles as azide surrogates in click reaction: efficient synthesis of N-heterocycle-substituted 1,2,3-triazoles.

ABSTRACT: It has been shown that various pyrido-, quinolino-, pyrazino-, and quinoxalinotetrazoles can be used efficiently as azide components in Cu-catalyzed click reaction with alkynes. This method allows for efficient synthesis of a wide variety of N-heterocyclic derivatives of 1,2,3-triazoles.

SUBMITTER: Chattopadhyay B 

PROVIDER: S-EPMC2862078 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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Fused tetrazoles as azide surrogates in click reaction: efficient synthesis of N-heterocycle-substituted 1,2,3-triazoles.

Chattopadhyay Buddhadeb B   Vera Claudia I Rivera CI   Chuprakov Stepan S   Gevorgyan Vladimir V  

Organic letters 20100501 9

It has been shown that various pyrido-, quinolino-, pyrazino-, and quinoxalinotetrazoles can be used efficiently as azide components in Cu-catalyzed click reaction with alkynes. This method allows for efficient synthesis of a wide variety of N-heterocyclic derivatives of 1,2,3-triazoles. ...[more]

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