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ABSTRACT:
SUBMITTER: Castillo JC
PROVIDER: S-EPMC7689893 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Castillo Juan-Carlos JC Bravo Nestor-Fabian NF Tamayo Lenka-Victoria LV Mestizo Paula-Daniela PD Hurtado John J Macías Mario M Portilla Jaime J
ACS omega 20201112 46
A new monophosphine Cu(I) complex bearing <i>bis</i>(pyrazolyl)methane (<b>L</b> <sub><b>1</b></sub> ) (<b>CuIL</b> <sub><b>1</b></sub> <b>PPh</b> <sub><b>3</b></sub> ) was synthesized and used as a catalyst for the three-component click reaction from an alkyl halide, sodium azide, and terminal alkyne to furnish 1,4-disubstituted 1,2,3-triazoles in up to 93% yield. The catalyst is highly stable, compatible with oxygen/water, and works with total efficiency under ultrasonic condition. The structu ...[more]