Ontology highlight
ABSTRACT:
SUBMITTER: Mason MR
PROVIDER: S-EPMC2862541 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Mason Matthew R J MR Ehlert Erich M E EM Eggers Ruben R Pool Chris W CW Hermening Stephan S Huseinovic Angelina A Timmermans Eric E Blits Bas B Verhaagen Joost J
Molecular therapy : the journal of the American Society of Gene Therapy 20100223 4
For many experiments in the study of the peripheral nervous system, it would be useful to genetically manipulate primary sensory neurons. We have compared vectors based on adeno-associated virus (AAV) serotypes 1, 2, 3, 4, 5, 6, and 8, and lentivirus (LV), all expressing green fluorescent protein (GFP), for efficiency of transduction of sensory neurons, expression level, cellular tropism, and persistence of transgene expression following direct injection into the dorsal root ganglia (DRG), using ...[more]