Ontology highlight
ABSTRACT:
SUBMITTER: Tu Y
PROVIDER: S-EPMC2866159 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Journal of natural products 20100401 4
The development of an automated, high-throughput fractionation procedure to prepare and analyze natural product libraries for drug discovery screening is described. Natural products obtained from plant materials worldwide were extracted and first prefractionated on polyamide solid-phase extraction cartridges to remove polyphenols, followed by high-throughput automated fractionation, drying, weighing, and reformatting for screening and storage. The analysis of fractions with UPLC coupled with MS, ...[more]