Ontology highlight
ABSTRACT:
SUBMITTER: Mitra M
PROVIDER: S-EPMC2866575 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Mitra Moutushy M Kandalam Mallikarjuna M Verma Rama Shanker RS UmaMaheswari Krishnan K Krishnakumar Subramanian S
Molecular vision 20100511
<h4>Purpose</h4>Previously we showed that epithelial cell adhesion molecule (Ep-CAM), a cell surface molecule, was highly expressed in primary retinoblastoma tumors. In the present study, we studied the genes regulated by Ep-CAM in a retinoblastoma Y79 cell line in vitro using a combination of short interference RNA and microarray technology.<h4>Methods</h4>Flow cytometry, quantitative reverse transcriptase PCR (Q-RT-PCR), and immunohistochemistry were performed to confirm the Ep-CAM re-expressi ...[more]