Genome sequence of Aedes aegypti, a major arbovirus vector.
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ABSTRACT:
SUBMITTER: Nene V
PROVIDER: S-EPMC2868357 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Publications
Genome sequence of Aedes aegypti, a major arbovirus vector.
Nene Vishvanath V Wortman Jennifer R JR Lawson Daniel D Haas Brian B Kodira Chinnappa C Tu Zhijian Jake ZJ Loftus Brendan B Xi Zhiyong Z Megy Karyn K Grabherr Manfred M Ren Quinghu Q Zdobnov Evgeny M EM Lobo Neil F NF Campbell Kathryn S KS Brown Susan E SE Bonaldo Maria F MF Zhu Jingsong J Sinkins Steven P SP Hogenkamp David G DG Amedeo Paolo P Arensburger Peter P Atkinson Peter W PW Bidwell Shelby S Biedler Jim J Birney Ewan E Bruggner Robert V RV Costas Javier J Coy Monique R MR Crabtree Jonathan J Crawford Matt M Debruyn Becky B Decaprio David D Eiglmeier Karin K Eisenstadt Eric E El-Dorry Hamza H Gelbart William M WM Gomes Suely L SL Hammond Martin M Hannick Linda I LI Hogan James R JR Holmes Michael H MH Jaffe David D Johnston J Spencer JS Kennedy Ryan C RC Koo Hean H Kravitz Saul S Kriventseva Evgenia V EV Kulp David D Labutti Kurt K Lee Eduardo E Li Song S Lovin Diane D DD Mao Chunhong C Mauceli Evan E Menck Carlos F M CF Miller Jason R JR Montgomery Philip P Mori Akio A Nascimento Ana L AL Naveira Horacio F HF Nusbaum Chad C O'leary Sinéad S Orvis Joshua J Pertea Mihaela M Quesneville Hadi H Reidenbach Kyanne R KR Rogers Yu-Hui YH Roth Charles W CW Schneider Jennifer R JR Schatz Michael M Shumway Martin M Stanke Mario M Stinson Eric O EO Tubio Jose M C JM Vanzee Janice P JP Verjovski-Almeida Sergio S Werner Doreen D White Owen O Wyder Stefan S Zeng Qiandong Q Zhao Qi Q Zhao Yongmei Y Hill Catherine A CA Raikhel Alexander S AS Soares Marcelo B MB Knudson Dennis L DL Lee Norman H NH Galagan James J Salzberg Steven L SL Paulsen Ian T IT Dimopoulos George G Collins Frank H FH Birren Bruce B Fraser-Liggett Claire M CM Severson David W DW
Science (New York, N.Y.) 20070517 5832
We present a draft sequence of the genome of Aedes aegypti, the primary vector for yellow fever and dengue fever, which at approximately 1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae. Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of approximately 4 to 6 increase in average gene length and in sizes of intergenic regions relative to An. gambiae and Drosophila melanogaster. Nonetheless, ...[more]
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