Improved reference genome of Aedes aegypti informs arbovirus vector control.
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ABSTRACT:
SUBMITTER: Matthews BJ
PROVIDER: S-EPMC6421076 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Improved reference genome of Aedes aegypti informs arbovirus vector control.
Matthews Benjamin J BJ Dudchenko Olga O Kingan Sarah B SB Koren Sergey S Antoshechkin Igor I Crawford Jacob E JE Glassford William J WJ Herre Margaret M Redmond Seth N SN Rose Noah H NH Weedall Gareth D GD Wu Yang Y Batra Sanjit S SS Brito-Sierra Carlos A CA Buckingham Steven D SD Campbell Corey L CL Chan Saki S Cox Eric E Evans Benjamin R BR Fansiri Thanyalak T Filipović Igor I Fontaine Albin A Gloria-Soria Andrea A Hall Richard R Joardar Vinita S VS Jones Andrew K AK Kay Raissa G G RGG Kodali Vamsi K VK Lee Joyce J Lycett Gareth J GJ Mitchell Sara N SN Muehling Jill J Murphy Michael R MR Omer Arina D AD Partridge Frederick A FA Peluso Paul P Aiden Aviva Presser AP Ramasamy Vidya V Rašić Gordana G Roy Sourav S Saavedra-Rodriguez Karla K Sharan Shruti S Sharma Atashi A Smith Melissa Laird ML Turner Joe J Weakley Allison M AM Zhao Zhilei Z Akbari Omar S OS Black William C WC Cao Han H Darby Alistair C AC Hill Catherine A CA Johnston J Spencer JS Murphy Terence D TD Raikhel Alexander S AS Sattelle David B DB Sharakhov Igor V IV White Bradley J BJ Zhao Li L Aiden Erez Lieberman EL Mann Richard S RS Lambrechts Louis L Powell Jeffrey R JR Sharakhova Maria V MV Tu Zhijian Z Robertson Hugh M HM McBride Carolyn S CS Hastie Alex R AR Korlach Jonas J Neafsey Daniel E DE Phillippy Adam M AM Vosshall Leslie B LB
Nature 20181114 7732
Female Aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress in understanding the biology of mosquitoes and developing the tools to fight them has been slowed by the lack of a high-quality genome assembly. Here we combine diverse technologies to produce the markedly improved, fully re-annotated AaegL5 genome assembly, and demonstrate how it accelerates mosquito science. We anchored phys ...[more]
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