Ontology highlight
ABSTRACT:
SUBMITTER: Xu Q
PROVIDER: S-EPMC2868511 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Xu Qing Q Guo Lihua L Moore Holly H Waclaw Ronald R RR Campbell Kenneth K Anderson Stewart A SA
Neuron 20100201 3
Interneurons in the cerebral cortex regulate cortical functions through the actions of distinct subgroups that express parvalbumin, somatostatin, or calretinin. The genesis of the first two subgroups requires the expression of NKX2.1, which is maintained by SHH signaling during neurogenesis. In this paper, we report that mosaic elimination in the medial ganglionic eminence (MGE) of Smo, a key effector of SHH signaling, reveals that MGE progenitors retain a remarkable degree of plasticity during ...[more]