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Vibrio chromosomes share common history.

ABSTRACT:

Background

While most gamma proteobacteria have a single circular chromosome, Vibrionales have two circular chromosomes. Horizontal gene transfer is common among Vibrios, and in light of this genetic mobility, it is an open question to what extent the two chromosomes themselves share a common history since their formation.

Results

Single copy genes from each chromosome (142 genes from chromosome I and 42 genes from chromosome II) were identified from 19 sequenced Vibrionales genomes and their phylogenetic comparison suggests consistent phylogenies for each chromosome. Additionally, study of the gene organization and phylogeny of the respective origins of replication confirmed the shared history.

Conclusions

Thus, while elements within the chromosomes may have experienced significant genetic mobility, the backbones share a common history. This allows conclusions based on multilocus sequence analysis (MLSA) for one chromosome to be applied equally to both chromosomes.

SUBMITTER: Kirkup BC

PROVIDER: S-EPMC2875227 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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Vibrio chromosomes share common history.

Kirkup Benjamin C BC Chang LeeAnn L Chang Sarah S Gevers Dirk D Polz Martin F MF Polz Martin F MF

BMC microbiology 20100510

<h4>Background</h4>While most gamma proteobacteria have a single circular chromosome, Vibrionales have two circular chromosomes. Horizontal gene transfer is common among Vibrios, and in light of this genetic mobility, it is an open question to what extent the two chromosomes themselves share a common history since their formation.<h4>Results</h4>Single copy genes from each chromosome (142 genes from chromosome I and 42 genes from chromosome II) were identified from 19 sequenced Vibrionales genom ...[more]

PMID: 20459749

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