Ontology highlight
ABSTRACT:
SUBMITTER: Nakamura T
PROVIDER: S-EPMC5161576 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Nakamura Tetsuya T Gehrke Andrew R AR Lemberg Justin J Szymaszek Julie J Shubin Neil H NH
Nature 20160817 7619
Understanding the evolutionary transformation of fish fins into tetrapod limbs is a fundamental problem in biology. The search for antecedents of tetrapod digits in fish has remained controversial because the distal skeletons of limbs and fins differ structurally, developmentally, and histologically. Moreover, comparisons of fins with limbs have been limited by a relative paucity of data on the cellular and molecular processes underlying the development of the fin skeleton. Here, we provide a fu ...[more]