Ontology highlight
ABSTRACT:
SUBMITTER: Lall GS
PROVIDER: S-EPMC2875410 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Lall Gurprit S GS Revell Victoria L VL Momiji Hiroshi H Al Enezi Jazi J Altimus Cara M CM Güler Ali D AD Aguilar Carlos C Cameron Morven A MA Allender Susan S Hankins Mark W MW Lucas Robert J RJ
Neuron 20100501 3
Photoreceptive, melanopsin-expressing retinal ganglion cells (mRGCs) encode ambient light (irradiance) for the circadian clock, the pupillomotor system, and other influential behavioral/physiological responses. mRGCs are activated both by their intrinsic phototransduction cascade and by the rods and cones. However, the individual contribution of each photoreceptor class to irradiance responses remains unclear. We address this deficit using mice expressing human red cone opsin, in which rod-, con ...[more]