Ontology highlight
ABSTRACT:
SUBMITTER: Emerson MM
PROVIDER: S-EPMC3819454 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Emerson Mark M MM Surzenko Natalia N Goetz Jillian J JJ Trimarchi Jeffrey J Cepko Constance L CL
Developmental cell 20130701 1
Cone photoreceptors carry out phototransduction in daylight conditions and provide the critical first step in color vision. Despite their importance, little is known about the developmental mechanisms involved in their generation, particularly how they are determined relative to rod photoreceptors, the cells that initiate vision in dim light. Here, we report the identification of a cis-regulatory module (CRM) for the thyroid hormone receptor beta (Thrb) gene, an early cone marker. We found that ...[more]