Involvement of the mannose phosphotransferase system of Lactobacillus plantarum WCFS1 in peroxide stress tolerance.
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SUBMITTER: Stevens MJ
PROVIDER: S-EPMC2876449 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
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Involvement of the mannose phosphotransferase system of Lactobacillus plantarum WCFS1 in peroxide stress tolerance.
Stevens Marc J A MJ Molenaar Douwe D de Jong Anne A de Vos Willem M WM Kleerebezem Michiel M
Applied and environmental microbiology 20100402 11
A Lactobacillus plantarum strain with a deletion in the gene rpoN, encoding the alternative sigma factor 54 (sigma(54)), displayed a 100-fold-higher sensitivity to peroxide than its parental strain. This feature could be due to sigma(54)-dependent regulation of genes involved in the peroxide stress response. However, transcriptome analyses of the wild type and the mutant strain during peroxide exposure did not support such a role for sigma(54). Subsequent experiments revealed that the impaired e ...[more]
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