Ontology highlight
ABSTRACT:
SUBMITTER: Rohde C
PROVIDER: S-EPMC2877691 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Rohde Christian C Zhang Yingying Y Reinhardt Richard R Jeltsch Albert A
BMC bioinformatics 20100506
<h4>Background</h4>Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA molecules are usually analyzed, to determine the methylation status at single CpG sites and molecule resolution.<h4>Results</h4>The BISMA (Bisulfite Sequencing DNA Methylation Analysis) software for analysis of primary bisulfite sequencing data implements sequencing data extraction and enhanced data processing, q ...[more]