Ontology highlight
ABSTRACT:
SUBMITTER: Bettinger CJ
PROVIDER: S-EPMC2880180 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Bettinger Christopher J CJ Bruggeman Joost P JP Borenstein Jeffrey T JT Langer Robert S RS
Biomaterials 20080304 15
Currently available synthetic biodegradable elastomers are primarily composed of crosslinked aliphatic polyesters, which suffer from deficiencies including (1) high crosslink densities, which results in exceedingly high stiffness, (2) rapid degradation upon implantation, or (3) limited chemical moieties for chemical modification. Herein, we have developed poly(1,3-diamino-2-hydroxypropane-co-polyol sebacate)s, a new class of synthetic, biodegradable elastomeric poly(ester amide)s composed of cro ...[more]