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Copper-catalyzed cyanation of heterocycle carbon-hydrogen bonds.

ABSTRACT: A method for regioselective cyanation of heterocycles has been developed. A number of aromatic heterocycles as well as azulene can be cyanated in reasonable to good yields by using a copper cyanide catalyst and an iodine oxidant.

SUBMITTER: Do HQ 

PROVIDER: S-EPMC2881224 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature

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Copper-catalyzed cyanation of heterocycle carbon-hydrogen bonds.

Do Hien-Quang HQ   Daugulis Olafs O  

Organic letters 20100601 11

A method for regioselective cyanation of heterocycles has been developed. A number of aromatic heterocycles as well as azulene can be cyanated in reasonable to good yields by using a copper cyanide catalyst and an iodine oxidant. ...[more]

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