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Programmed subcellular release for studying the dynamics of cell detachment.

ABSTRACT: Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level.

SUBMITTER: Wildt B

PROVIDER: S-EPMC2882093 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature

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Programmed subcellular release for studying the dynamics of cell detachment.

Wildt Bridget B Wirtz Denis D Searson Peter C PC

Nature methods 20090201 3

Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level. ...[more]

PMID: 19182793

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