Ontology highlight
ABSTRACT:
SUBMITTER: Duan S
PROVIDER: S-EPMC2882201 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Duan Shaofeng S Jana Ranjan R Tunge Jon A JA
The Journal of organic chemistry 20090601 12
Herein we report that simple Lewis acids catalyze the hydroarylation of benzylidene malonates with phenols. Ultimately, 3,4-disubstituted dihydrocoumarins are obtained via a hydroarylation-lactonization sequence. Moreover, the dihydrocoumarins are formed with a high degree of diastereoselectivity favoring the trans stereoisomer. ...[more]