Ontology highlight
ABSTRACT:
SUBMITTER: Panayotopoulou EG
PROVIDER: S-EPMC2884518 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Panayotopoulou Effrosini G EG Sgouras Dionyssios N DN Papadakos Konstantinos S KS Petraki Kalliopi K Breurec Sébastien S Michopoulos Spyros S Mantzaris Gerassimos G Papatheodoridis George G Mentis Andreas A Archimandritis Athanasios A
Journal of clinical microbiology 20100414 6
Polymorphic variability in Helicobacter pylori factors CagA and VacA contributes to bacterial virulence. The presence of one CagA EPIYA-C site is an independent risk factor for gastroduodenal ulceration (odds ratio [OR], 4.647; 95% confidence interval [CI], 2.037 to 10.602), while the presence of the vacA i1 allele is a risk factor for increased activity (OR, 5.310; 95% CI, 2.295 to 12.287) and severity of gastritis (OR, 3.862; 95% CI, 1.728 to 8.632). ...[more]