Ontology highlight
ABSTRACT:
SUBMITTER: Miftahussurur M
PROVIDER: S-EPMC5332543 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Expert review of gastroenterology & hepatology 20151016 12
Helicobacter pylori infection plays an important role in the pathogenesis of peptic ulcer disease (PUD). Several factors have been proposed as possible H. pylori virulence determinants; for example, bacterial adhesins and gastric inflammation factors are associated with an increased risk of PUD. However, differences in bacterial virulence factors alone cannot explain the opposite ends of the PUD disease spectrum, that is duodenal and gastric ulcers; presumably, both bacterial and host factors co ...[more]