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Genetics of psoriasis and psoriatic arthritis.


ABSTRACT: It is well established that psoriasis and psoriatic arthritis (PsA) have a strong genetic component. Recent advances in genetics have confirmed previous associations and new loci have been discovered. However, these loci do not fully account for the high heritability of psoriasis and PsA and therefore many genetic as well as environmental factors remain to be identified. This paper reviews the current status of genetic studies in psoriasis and PsA.

SUBMITTER: Chandran V 

PROVIDER: S-EPMC2887520 | biostudies-literature | 2010 Apr-Jun

REPOSITORIES: biostudies-literature

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Genetics of psoriasis and psoriatic arthritis.

Chandran Vinod V  

Indian journal of dermatology 20100401 2


It is well established that psoriasis and psoriatic arthritis (PsA) have a strong genetic component. Recent advances in genetics have confirmed previous associations and new loci have been discovered. However, these loci do not fully account for the high heritability of psoriasis and PsA and therefore many genetic as well as environmental factors remain to be identified. This paper reviews the current status of genetic studies in psoriasis and PsA. ...[more]

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