Ontology highlight
ABSTRACT:
SUBMITTER: He Y
PROVIDER: S-EPMC2887669 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
He Yangdong Y Hua Ya Y Lee Jin-Yul JY Liu Wenquan W Keep Richard F RF Wang Michael M MM Xi Guohua G
Translational stroke research 20100301 1
Our recent study has demonstrated that hemoglobin (Hb) is present in cerebral neurons and neuronal Hb is inducible after cerebral ischemia. In the present study, we examined the effects of intracerebral hemorrhage (ICH) on the mRNA levels of the α-globin (HbA) and the β-globin (HbB) components of Hb and Hb protein in the brain in vivo and in vitro. In vivo, male Sprague-Dawley rats received either a needle insertion (sham) or an infusion of autologous whole blood into the basal ganglia and were ...[more]