Ontology highlight
ABSTRACT:
SUBMITTER: Ramakrishnan L
PROVIDER: S-EPMC2888401 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Ramakrishnan Latha L Muller-Steffner Hélène H Bosc Christophe C Vacquier Victor D VD Schuber Francis F Moutin Marie-Jo MJ Dale Leslie L Patel Sandip S
The Journal of biological chemistry 20100412 26
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate are ubiquitous calcium-mobilizing messengers produced by the same family of multifunctional enzymes, the ADP-ribosyl cyclases. Not all ADP-ribosyl cyclases have been identified, and how production of different messengers is achieved is incompletely understood. Here, we report the cloning and characterization of a novel ADP-ribosyl cyclase (SpARC4) from the sea urchin, a key model organism for the study of calcium-signaling pathw ...[more]