Ontology highlight
ABSTRACT:
SUBMITTER: Charbonneau NL
PROVIDER: S-EPMC2888437 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Charbonneau Noe L NL Jordan C Diana CD Keene Douglas R DR Lee-Arteaga Sui S Dietz Harry C HC Rifkin Daniel B DB Ramirez Francesco F Sakai Lynn Y LY
The Journal of biological chemistry 20100419 26
Fibrillin microfibrils are polymeric structures present in connective tissues. The importance of fibrillin microfibrils to connective tissue function has been demonstrated by the multiple genetic disorders caused by mutations in fibrillins and in microfibril-associated molecules. However, knowledge of microfibril structure is limited, largely due to their insolubility. Most previous studies have focused on how fibrillin-1 is organized within microfibril polymers. In this study, an immunochemical ...[more]