Imaging genetics of structural brain connectivity and neural integrity markers.
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ABSTRACT:
SUBMITTER: Marenco S
PROVIDER: S-EPMC2889028 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Publications
Imaging genetics of structural brain connectivity and neural integrity markers.
Marenco Stefano S Radulescu Eugenia E
NeuroImage 20091122 3
We review studies that have used diffusion imaging (DI) and magnetic resonance spectroscopy (MRS) to investigate genetic associations. A brief description of the measures obtainable with these methods and of some methodological and interpretability limitations is given. The usefulness of DI and MRS in defining intermediate phenotypes and in demonstrating the effects of common genetic variants known to increase risk for psychiatric manifestations on anatomical and metabolic phenotypes is reviewed ...[more]
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