Ontology highlight
ABSTRACT:
SUBMITTER: Dummer R
PROVIDER: S-EPMC2889748 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Dummer Reinhard R Eichmüller Stefan S Gellrich Sylke S Assaf Chalid C Dreno Brigitte B Schiller Meinhard M Dereure Olivier O Baudard Marion M Bagot Martine M Khammari Amir A Bleuzen Pascal P Bataille Vincent V Derbij Anna A Wiedemann Nicole N Waterboer Tim T Lusky Monika M Acres Bruce B Urosevic-Maiwald Mirjana M
Molecular therapy : the journal of the American Society of Gene Therapy 20100406 6
Cutaneous lymphomas (CLs) are a heterogeneous group of lymphoproliferative disorders that are manageable by immunotherapy. Twenty-one patients were enrolled in a prospective open-label, dose-escalation multicenter study evaluating the effects of repeated TG1042 [adenovirus-interferon (IFN)-gamma] intralesional injections in patients with primary CLs, of which 18 were of T-cell and 3 of B-cell type. Repeated intralesional therapy using TG1042 consistently results in local tumor regressions in abo ...[more]