In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs.
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ABSTRACT:
SUBMITTER: Davies SJ
PROVIDER: S-EPMC2891237 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Publications
In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs.
Davies Stephen J SJ Smith Steven J SJ Lim K C KC Zhang Hongbing H Purchio Anthony F AF McKerrow James H JH West David B DB
International journal for parasitology 20050701 8
Using a sensitive transgenic reporter mouse system and in vivo biophotonic imaging techniques, we present a dynamic analysis of eosinophil responses to schistosome infection. Use of this methodology provided previously unattainable detail on the spatial and temporal distribution of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs. Dramatic hepatic and intestinal eosinophilia in response to the deposition of schistosome eggs, with accompanying eosinopoiesis in the bon ...[more]
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