Ontology highlight
ABSTRACT:
SUBMITTER: Canterbury DP
PROVIDER: S-EPMC2892691 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Canterbury Daniel P DP Micalizio Glenn C GC
Journal of the American Chemical Society 20100601 22
A reaction sequence composed of regioselective formal hydroalkynylation, reductive ene-yne cross-coupling, and oxidative cyclization has been developed to prepare stereochemically dense spiroketals. Overall, the chemistry defines a three-component coupling process for the union of two homoallylic alcohol-based substrates with trimethylsilylacetylene. ...[more]