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FuncBase: a resource for quantitative gene function annotation.

ABSTRACT: Computational gene function prediction can serve to focus experimental resources on high-priority experimental tasks. FuncBase is a web resource for viewing quantitative machine learning-based gene function annotations. Quantitative annotations of genes, including fungal and mammalian genes, with Gene Ontology terms are accompanied by a community feedback system. Evidence underlying function annotations is shown. For example, a custom Cytoscape viewer shows functional linkage graphs relevant to the gene or function of interest. FuncBase provides links to external resources, and may be accessed directly or via links from species-specific databases.FuncBase as well as all underlying data and annotations are freely available via http://func.med.harvard.edu/

SUBMITTER: Beaver JE

PROVIDER: S-EPMC2894510 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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FuncBase: a resource for quantitative gene function annotation.

Beaver John E JE Tasan Murat M Gibbons Francis D FD Tian Weidong W Hughes Timothy R TR Roth Frederick P FP

Bioinformatics (Oxford, England) 20100521 14

<h4>Summary</h4>Computational gene function prediction can serve to focus experimental resources on high-priority experimental tasks. FuncBase is a web resource for viewing quantitative machine learning-based gene function annotations. Quantitative annotations of genes, including fungal and mammalian genes, with Gene Ontology terms are accompanied by a community feedback system. Evidence underlying function annotations is shown. For example, a custom Cytoscape viewer shows functional linkage gra ...[more]

PMID: 20495000

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