Inward rotating spiral waves in glycolysis.
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ABSTRACT:
SUBMITTER: Straube R
PROVIDER: S-EPMC2895376 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Publications
Inward rotating spiral waves in glycolysis.
Straube Ronny R Vermeer Satenik S Nicola Ernesto M EM Mair Thomas T
Biophysical journal 20100701 1
We report on the first observation of inward rotating spiral waves (antispirals) in a biochemical reaction-diffusion system. Experiments are performed with extracts from yeast cells in an open spatial reactor. By increasing the protein concentration of the extract we observe a transition from outward to inward propagating waves of glycolytic activity. Numerical simulations with an allosteric model for the phosphofructokinase can reproduce these inward propagating waves over a wide range of param ...[more]
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