Ontology highlight
ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC4413915 | biostudies-literature | 2004 Nov
REPOSITORIES: biostudies-literature
Huang Xiaoying X Troy William C WC Yang Qian Q Ma Hongtao H Laing Carlo R CR Schiff Steven J SJ Wu Jian-Young JY
The Journal of neuroscience : the official journal of the Society for Neuroscience 20041101 44
Spiral waves are a basic feature of excitable systems. Although such waves have been observed in a variety of biological systems, they have not been observed in the mammalian cortex during neuronal activity. Here, we report stable rotating spiral waves in rat neocortical slices visualized by voltage-sensitive dye imaging. Tissue from the occipital cortex (visual) was sectioned parallel to cortical lamina to preserve horizontal connections in layers III-V (500-mum-thick, approximately 4 x 6 mm(2) ...[more]