Transdermal rotigotine for the perioperative management of Parkinson's disease.

ABSTRACT: Continuous delivery of antiparkinsonian medication during a perioperative period is desirable to avoid 'off'-symptom complications in surgical patients with concomitant Parkinson's disease (PD). Fourteen PD patients undergoing surgery under general anesthesia were switched from oral dopaminergic medication to transdermally delivered 24-h rotigotine (median dose 12 mg/24 h) for the perioperative period. Rotigotine treatment was considered feasible by patients, their anesthesiologists and neurologists with good control of PD symptoms and easy switching and re-switching of PD medication.

SUBMITTER: Wullner U 

PROVIDER: S-EPMC2895903 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature