Ontology highlight
ABSTRACT:
SUBMITTER: Pagonabarraga J
PROVIDER: S-EPMC4352510 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Pagonabarraga Javier J Piñol Gerard G Cardozo Adriana A Sanz Pilar P Puente Víctor V Otermín Pilar P Legarda Inés I Delgado Tania T Serrano Carmen C Balaguer Ernest E Aguirregomozcorta María M Álvarez Ramiro R Kulisevsky Jaime J JJ
Parkinson's disease 20150222
Sleep disturbances occur frequently in patients with Parkinson's disease (PD). The aim of this study was to investigate the effects of rotigotine on sleep fluctuations in a sample of PD patients with self-reported complaints of nocturnal awakenings. This prospective, open-label, observational, and multicenter study enrolled consecutive outpatients with PD and administered rotigotine (mean dose 8.9 mg/day) for 3 months. The primary endpoint was the change from baseline in sleep fragmentation, ass ...[more]