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International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma.

ABSTRACT: An international multicenter study was conducted to assess the performance of a panel of simian immunodeficiency virus (SIV) RNA reference materials for plasma viral load determinations. Reliable quantification was demonstrated across an approximately 6 log(10) dynamic range. Availability of external reference materials will enable independent calibration of SIV plasma viral load assays.

SUBMITTER: Ham C

PROVIDER: S-EPMC2897500 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma.

Ham Claire C Srinivasan Priya P Thorstensson Rigmor R Verschoor Ernst E Fagrouche Zahra Z Sernicola Leonardo L Ramos Artur A Titti Fausto F Almond Neil N Berry Neil N

Journal of clinical microbiology 20100428 7

An international multicenter study was conducted to assess the performance of a panel of simian immunodeficiency virus (SIV) RNA reference materials for plasma viral load determinations. Reliable quantification was demonstrated across an approximately 6 log(10) dynamic range. Availability of external reference materials will enable independent calibration of SIV plasma viral load assays. ...[more]

PMID: 20427693

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