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International network of cancer genome projects.


ABSTRACT: The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

SUBMITTER: International Cancer Genome Consortium 

PROVIDER: S-EPMC2902243 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature

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International network of cancer genome projects.

Hudson Thomas J TJ   Anderson Warwick W   Artez Axel A   Barker Anna D AD   Bell Cindy C   Bernabé Rosa R RR   Bhan M K MK   Calvo Fabien F   Eerola Iiro I   Gerhard Daniela S DS   Guttmacher Alan A   Guyer Mark M   Hemsley Fiona M FM   Jennings Jennifer L JL   Kerr David D   Klatt Peter P   Kolar Patrik P   Kusada Jun J   Lane David P DP   Laplace Frank F   Youyong Lu L   Nettekoven Gerd G   Ozenberger Brad B   Peterson Jane J   Rao T S TS   Remacle Jacques J   Schafer Alan J AJ   Shibata Tatsuhiro T   Stratton Michael R MR   Vockley Joseph G JG   Watanabe Koichi K   Yang Huanming H   Yuen Matthew M F MM   Knoppers Bartha M BM   Bobrow Martin M   Cambon-Thomsen Anne A   Dressler Lynn G LG   Dyke Stephanie O M SO   Joly Yann Y   Kato Kazuto K   Kennedy Karen L KL   Nicolás Pilar P   Parker Michael J MJ   Rial-Sebbag Emmanuelle E   Romeo-Casabona Carlos M CM   Shaw Kenna M KM   Wallace Susan S   Wiesner Georgia L GL   Zeps Nikolajs N   Lichter Peter P   Biankin Andrew V AV   Chabannon Christian C   Chin Lynda L   Clément Bruno B   de Alava Enrique E   Degos Françoise F   Ferguson Martin L ML   Geary Peter P   Hayes D Neil DN   Hudson Thomas J TJ   Johns Amber L AL   Kasprzyk Arek A   Nakagawa Hidewaki H   Penny Robert R   Piris Miguel A MA   Sarin Rajiv R   Scarpa Aldo A   Shibata Tatsuhiro T   van de Vijver Marc M   Futreal P Andrew PA   Aburatani Hiroyuki H   Bayés Mónica M   Botwell David D L DD   Campbell Peter J PJ   Estivill Xavier X   Gerhard Daniela S DS   Grimmond Sean M SM   Gut Ivo I   Hirst Martin M   López-Otín Carlos C   Majumder Partha P   Marra Marco M   McPherson John D JD   Nakagawa Hidewaki H   Ning Zemin Z   Puente Xose S XS   Ruan Yijun Y   Shibata Tatsuhiro T   Stratton Michael R MR   Stunnenberg Hendrik G HG   Swerdlow Harold H   Velculescu Victor E VE   Wilson Richard K RK   Xue Hong H HH   Yang Liu L   Spellman Paul T PT   Bader Gary D GD   Boutros Paul C PC   Campbell Peter J PJ   Flicek Paul P   Getz Gad G   Guigó Roderic R   Guo Guangwu G   Haussler David D   Heath Simon S   Hubbard Tim J TJ   Jiang Tao T   Jones Steven M SM   Li Qibin Q   López-Bigas Nuria N   Luo Ruibang R   Muthuswamy Lakshmi L   Ouellette B F Francis BF   Pearson John V JV   Puente Xose S XS   Quesada Victor V   Raphael Benjamin J BJ   Sander Chris C   Shibata Tatsuhiro T   Speed Terence P TP   Stein Lincoln D LD   Stuart Joshua M JM   Teague Jon W JW   Totoki Yasushi Y   Tsunoda Tatsuhiko T   Valencia Alfonso A   Wheeler David A DA   Wu Honglong H   Zhao Shancen S   Zhou Guangyu G   Stein Lincoln D LD   Guigó Roderic R   Hubbard Tim J TJ   Joly Yann Y   Jones Steven M SM   Kasprzyk Arek A   Lathrop Mark M   López-Bigas Nuria N   Ouellette B F Francis BF   Spellman Paul T PT   Teague Jon W JW   Thomas Gilles G   Valencia Alfonso A   Yoshida Teruhiko T   Kennedy Karen L KL   Axton Myles M   Dyke Stephanie O M SO   Futreal P Andrew PA   Gerhard Daniela S DS   Gunter Chris C   Guyer Mark M   Hudson Thomas J TJ   McPherson John D JD   Miller Linda J LJ   Ozenberger Brad B   Shaw Kenna M KM   Kasprzyk Arek A   Stein Lincoln D LD   Zhang Junjun J   Haider Syed A SA   Wang Jianxin J   Yung Christina K CK   Cros Anthony A   Liang Yong Y   Gnaneshan Saravanamuttu S   Guberman Jonathan J   Hsu Jack J   Bobrow Martin M   Chalmers Don R C DR   Hasel Karl W KW   Joly Yann Y   Kaan Terry S H TS   Kennedy Karen L KL   Knoppers Bartha M BM   Lowrance William W WW   Masui Tohru T   Nicolás Pilar P   Rial-Sebbag Emmanuelle E   Rodriguez Laura Lyman LL   Vergely Catherine C   Yoshida Teruhiko T   Grimmond Sean M SM   Biankin Andrew V AV   Bowtell David D L DD   Cloonan Nicole N   deFazio Anna A   Eshleman James R JR   Etemadmoghadam Dariush D   Gardiner Brooke B BB   Kench James G JG   Scarpa Aldo A   Sutherland Robert L RL   Tempero Margaret A MA   Waddell Nicola J NJ   Wilson Peter J PJ   McPherson John D JD   Gallinger Steve S   Tsao Ming-Sound MS   Shaw Patricia A PA   Petersen Gloria M GM   Mukhopadhyay Debabrata D   Chin Lynda L   DePinho Ronald A RA   Thayer Sarah S   Muthuswamy Lakshmi L   Shazand Kamran K   Beck Timothy T   Sam Michelle M   Timms Lee L   Ballin Vanessa V   Lu Youyong Y   Ji Jiafu J   Zhang Xiuqing X   Chen Feng F   Hu Xueda X   Zhou Guangyu G   Yang Qi Q   Tian Geng G   Zhang Lianhai L   Xing Xiaofang X   Li Xianghong X   Zhu Zhenggang Z   Yu Yingyan Y   Yu Jun J   Yang Huanming H   Lathrop Mark M   Tost Jörg J   Brennan Paul P   Holcatova Ivana I   Zaridze David D   Brazma Alvis A   Egevard Lars L   Prokhortchouk Egor E   Banks Rosamonde Elizabeth RE   Uhlén Mathias M   Cambon-Thomsen Anne A   Viksna Juris J   Ponten Fredrik F   Skryabin Konstantin K   Stratton Michael R MR   Futreal P Andrew PA   Birney Ewan E   Borg Ake A   Børresen-Dale Anne-Lise AL   Caldas Carlos C   Foekens John A JA   Martin Sancha S   Reis-Filho Jorge S JS   Richardson Andrea L AL   Sotiriou Christos C   Stunnenberg Hendrik G HG   Thoms Giles G   van de Vijver Marc M   van't Veer Laura L   Calvo Fabien F   Birnbaum Daniel D   Blanche Hélène H   Boucher Pascal P   Boyault Sandrine S   Chabannon Christian C   Gut Ivo I   Masson-Jacquemier Jocelyne D JD   Lathrop Mark M   Pauporté Iris I   Pivot Xavier X   Vincent-Salomon Anne A   Tabone Eric E   Theillet Charles C   Thomas Gilles G   Tost Jörg J   Treilleux Isabelle I   Calvo Fabien F   Bioulac-Sage Paulette P   Clément Bruno B   Decaens Thomas T   Degos Françoise F   Franco Dominique D   Gut Ivo I   Gut Marta M   Heath Simon S   Lathrop Mark M   Samuel Didier D   Thomas Gilles G   Zucman-Rossi Jessica J   Lichter Peter P   Eils Roland R   Brors Benedikt B   Korbel Jan O JO   Korshunov Andrey A   Landgraf Pablo P   Lehrach Hans H   Pfister Stefan S   Radlwimmer Bernhard B   Reifenberger Guido G   Taylor Michael D MD   von Kalle Christof C   Majumder Partha P PP   Sarin Rajiv R   Rao T S TS   Bhan M K MK   Scarpa Aldo A   Pederzoli Paolo P   Lawlor Rita A RA   Delledonne Massimo M   Bardelli Alberto A   Biankin Andrew V AV   Grimmond Sean M SM   Gress Thomas T   Klimstra David D   Zamboni Giuseppe G   Shibata Tatsuhiro T   Nakamura Yusuke Y   Nakagawa Hidewaki H   Kusada Jun J   Tsunoda Tatsuhiko T   Miyano Satoru S   Aburatani Hiroyuki H   Kato Kazuto K   Fujimoto Akihiro A   Yoshida Teruhiko T   Campo Elias E   López-Otín Carlos C   Estivill Xavier X   Guigó Roderic R   de Sanjosé Silvia S   Piris Miguel A MA   Montserrat Emili E   González-Díaz Marcos M   Puente Xose S XS   Jares Pedro P   Valencia Alfonso A   Himmelbauer Heinz H   Quesada Victor V   Bea Silvia S   Stratton Michael R MR   Futreal P Andrew PA   Campbell Peter J PJ   Vincent-Salomon Anne A   Richardson Andrea L AL   Reis-Filho Jorge S JS   van de Vijver Marc M   Thomas Gilles G   Masson-Jacquemier Jocelyne D JD   Aparicio Samuel S   Borg Ake A   Børresen-Dale Anne-Lise AL   Caldas Carlos C   Foekens John A JA   Stunnenberg Hendrik G HG   van't Veer Laura L   Easton Douglas F DF   Spellman Paul T PT   Martin Sancha S   Barker Anna D AD   Chin Lynda L   Collins Francis S FS   Compton Carolyn C CC   Ferguson Martin L ML   Gerhard Daniela S DS   Getz Gad G   Gunter Chris C   Guttmacher Alan A   Guyer Mark M   Hayes D Neil DN   Lander Eric S ES   Ozenberger Brad B   Penny Robert R   Peterson Jane J   Sander Chris C   Shaw Kenna M KM   Speed Terence P TP   Spellman Paul T PT   Vockley Joseph G JG   Wheeler David A DA   Wilson Richard K RK   Hudson Thomas J TJ   Chin Lynda L   Knoppers Bartha M BM   Lander Eric S ES   Lichter Peter P   Stein Lincoln D LD   Stratton Michael R MR   Anderson Warwick W   Barker Anna D AD   Bell Cindy C   Bobrow Martin M   Burke Wylie W   Collins Francis S FS   Compton Carolyn C CC   DePinho Ronald A RA   Easton Douglas F DF   Futreal P Andrew PA   Gerhard Daniela S DS   Green Anthony R AR   Guyer Mark M   Hamilton Stanley R SR   Hubbard Tim J TJ   Kallioniemi Olli P OP   Kennedy Karen L KL   Ley Timothy J TJ   Liu Edison T ET   Lu Youyong Y   Majumder Partha P   Marra Marco M   Ozenberger Brad B   Peterson Jane J   Schafer Alan J AJ   Spellman Paul T PT   Stunnenberg Hendrik G HG   Wainwright Brandon J BJ   Wilson Richard K RK   Yang Huanming H  

Nature 20100401 7291


The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic  ...[more]

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