Ontology highlight
ABSTRACT:
SUBMITTER: Risacher SL
PROVIDER: S-EPMC2904350 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Risacher Shannon L SL Shen Li L West John D JD Kim Sungeun S McDonald Brenna C BC Beckett Laurel A LA Harvey Danielle J DJ Jack Clifford R CR Weiner Michael W MW Saykin Andrew J AJ
Neurobiology of aging 20100801 8
Atrophic changes in early Alzheimer's disease (AD) and amnestic mild cognitive impairment (MCI) have been proposed as biomarkers for detection and monitoring. We analyzed magnetic resonance imaging (MRI) atrophy rate from baseline to 1 year in 4 groups of participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI): AD (n = 152), converters from MCI to probable AD (MCI-C, n = 60), stable MCI (MCI-S, n = 261), and healthy controls (HC, n = 200). Scans were analyzed using multiple meth ...[more]