Ontology highlight
ABSTRACT:
SUBMITTER: Jiang H
PROVIDER: S-EPMC2908677 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Jiang Huifeng H Guan Wenjun W Gu Zhenglong Z
PLoS genetics 20100722 7
Genome-wide studies of post-transcriptional mRNA regulation in model organisms indicate a "post-transcriptional RNA regulon" model, in which a set of functionally related genes is regulated by mRNA-binding RNAs or proteins. One well-studied post-transcriptional regulon by Puf3p functions in mitochondrial biogenesis in budding yeast. The evolution of the Puf3p regulon remains unclear because previous studies have shown functional divergence of Puf3p regulon targets among yeast, fruit fly, and hum ...[more]