Global fitness profiling of fission yeast deletion strains by barcode sequencing.
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ABSTRACT:
SUBMITTER: Han TX
PROVIDER: S-EPMC2911108 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Publications
Global fitness profiling of fission yeast deletion strains by barcode sequencing.
Han Tian Xu TX Xu Xing-Ya XY Zhang Mei-Jun MJ Peng Xu X Du Li-Lin LL
Genome biology 20100610 6
A genome-wide deletion library is a powerful tool for probing gene functions and one has recently become available for the fission yeast Schizosaccharomyces pombe. Here we use deep sequencing to accurately characterize the barcode sequences in the deletion library, thus enabling the quantitative measurement of the fitness of fission yeast deletion strains by barcode sequencing. ...[more]
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